ECM Atlas
A technical reference on materials that act on the dermal extracellular matrix.
Regulatory identity across markets
The same material is classified differently from market to market. This table is the reason this site exists.
| Material | KR | EU | US | JP | CN | VN |
|---|---|---|---|---|---|---|
| Biostimulator — aliphatic polyester | ||||||
| PCL (Polycaprolactone) A synthetic biodegradable polyester used as a dermal biostimulatory material. It has a low melting point and a slow hydrolytic breakdown that the literature describes as longer than for lactic-acid-based polyesters. | MD | MD | — | — | — | — |
| PDLLA (Poly-D,L-lactic acid) A synthetic biodegradable polyester used as a dermal biostimulatory material. Being racemic, it is amorphous rather than semi-crystalline, and hydrolyses to lactic acid monomers over time. | MD | MD | — | — | — | — |
| PLLA (Poly-L-lactic acid) A synthetic biodegradable polyester used as a dermal biostimulatory material. Unlike the racemic form, it is built from a single stereoisomer and is semi-crystalline, which is associated with slower hydrolytic breakdown. | MD | MD | MD | — | — | — |
| Biostimulator — ceramic microsphere | ||||||
| CaHA (Calcium hydroxylapatite) A calcium phosphate ceramic used as a dermal biostimulatory material. The mineral phase is chemically identical to the inorganic component of bone. | MD | MD | — | — | — | — |
| Nucleotide-derived agent | ||||||
| PDRN (Polydeoxyribonucleotide) A mixture of DNA-derived polymer fragments, typically of marine origin, used in wound and skin applications. Distinct from the polymer biostimulators in that it is not a particulate scaffold. | — | — | — | — | — | — |
COS cosmetic · MD medical device · RX drug · — not established in public sources