CaHA (Calcium hydroxylapatite)
This document is technical information about materials. It does not recommend any procedure or product.
In brief
A calcium phosphate ceramic used as a dermal biostimulatory material. The mineral phase is chemically identical to the inorganic component of bone.
Regulatory identity by market
COS cosmetic · MD medical device · RX drug · — not established in public sources
Identity & physical properties
| Synonyms | Calcium hydroxylapatite, Calcium hydroxyapatite, CaHA |
|---|---|
| Formula | Ca10(PO4)6(OH)2 |
| Family | Biostimulator — ceramic microsphere |
| Particle size | Reported in the tens of micrometres; a comparative morphology study places CaHA and PLLA particles side by side |
| Morphology | Smooth spherical ceramic particles suspended in a carrier gel |
Mechanism
Reviews describe particles acting as a scaffold with subsequent fibroblast response and matrix deposition. A systematic review has catalogued the reported skin-regeneration mechanisms.
Evidence
Regulatory identity — detail
| Market | Classification | Note | Basis |
|---|---|---|---|
| KR | medical-device | Injectable forms follow the tissue-repair biomaterial route in the MFDS device classification notice. | Legal text |
| EU | medical-device | Annex XVI, Section 3 of the MDR covers substances intended for facial or other dermal filling by injection, bringing such products under the Regulation even without an intended medical purpose. | Legal text |
| US | unclassified | Product-level FDA classification not established from public sources as of the revision date below. | — |
| JP | unclassified | Not established from public sources as of the revision date below. | — |
| CN | unclassified | Not established from public sources as of the revision date below. | — |
| VN | unclassified | Not established from public sources as of the revision date below. | — |
Limitations & open questions
Much of the evidence base is narrative or systematic review rather than head-to-head randomised comparison. Dilution and layer of placement vary widely in practice and are not standardised in the literature.
All statements on this page are drawn from the cited literature. Where a market’s regulatory classification could not be established from public sources, it is marked as not established rather than inferred.